Strength Systematic Review 2015

Effect of adding single-joint exercises to a multi-joint exercise resistance-training program on strength and hypertrophy in untrained subjects

By Paulo Gentil, Saulo R.S. Soares and Martim Bottaro

Applied Physiology, Nutrition, and Metabolism, 40(10), pp. 1130-1134

Abstract

<h2>Abstract</h2> <p>This study investigated whether the addition of single-joint (SJ) isolation exercises to a multi-joint (MJ) resistance-training program confers additional benefits in terms of muscular strength and <a href="/terms/muscle-hypertrophy/" class="term-link" data-slug="muscle-hypertrophy" title="hypertrophy">hypertrophy</a> in untrained individuals. Forty young men were randomly assigned to either a multi-joint-only group (MJ) or a combined multi-joint plus single-joint group (MJ+SJ). Both groups trained three times per week for 10 weeks. Muscle <a href="/terms/cross-sectional-area/" class="term-link" data-slug="cross-sectional-area" title="cross-sectional area">cross-sectional area</a> (CSA) of the elbow flexors and extensors was assessed via ultrasound, and maximal dynamic strength was evaluated through <a href="/terms/one-repetition-maximum/" class="term-link" data-slug="one-repetition-maximum" title="one-<a href="/terms/repetition-maximum/" class="term-link" data-slug="repetition-maximum" title="repetition maximum">repetition maximum</a>">one-repetition maximum</a> (1RM) testing in the lat pulldown and triceps pushdown. Results demonstrated that both groups exhibited significant increases in muscle CSA and 1RM strength over the training period. Crucially, no statistically significant differences were observed between groups for either hypertrophy or strength outcomes. These findings suggest that, for untrained individuals, multi-joint exercises alone provide sufficient mechanical and metabolic stimuli to drive arm muscle growth and strength gains equivalent to those achieved with additional isolation work. The practical implication is that program designers and coaches working with beginners can achieve comparable results using time-efficient, <a href="/terms/compound-exercise/" class="term-link" data-slug="compound-exercise" title="compound movement">compound movement</a>-based protocols without the need to incorporate supplementary single-joint exercises [1].</p>

Introduction

Introduction

Resistance training programs are routinely designed around two fundamental categories of exercise: multi-joint (MJ) compound movements, which recruit multiple muscle groups and joints simultaneously, and single-joint (SJ) isolation movements, which target specific muscles with limited synergist involvement. Classic examples of MJ exercises include the bench press, squat, and barbell row, while SJ movements encompass the bicep curl, triceps extension, and leg extension. In practice, the vast majority of resistance training programs — whether designed for general fitness, bodybuilding, or athletic performance — incorporate both categories.

The prevailing rationale for including SJ exercises is the assumption that MJ movements fail to provide adequate direct stimulation to smaller synergist muscles, such as the elbow flexors and extensors, that assist during compound lifts. It is commonly believed that the lat pulldown, for instance, does not sufficiently challenge the biceps brachii in isolation and that dedicated curling exercises are necessary to fully develop arm musculature. However, the empirical basis for this assumption has not been rigorously tested in controlled experimental settings [1].

From a practical standpoint, the question carries meaningful implications for program design. Adding SJ exercises increases session volume, duration, and potential fatigue accumulation. For time-limited populations — recreational gym-goers, older adults, or individuals in rehabilitation settings — understanding whether isolation exercises offer measurable benefits beyond compound movements is essential for evidence-based programming. Similarly, for strength and conditioning coaches seeking to maximize training efficiency, the cost-benefit ratio of including SJ movements must be justified by demonstrable physiological outcomes [2].

This investigation aimed to address this gap by directly comparing MJ-only training to a combined MJ+SJ protocol in untrained men across a standardized 10-week program, measuring both hypertrophic and strength outcomes.

Methods

<h2>Methods</h2> <h3>Participants</h3> <p>Forty untrained young men (age: 22.7 ± 4.7 years; body mass: 73.7 ± 9.2 kg) were recruited and randomly allocated to one of two experimental groups. Participants were classified as untrained based on the absence of structured resistance training experience in the preceding six months. Exclusion criteria included musculoskeletal injury, cardiovascular contraindications, and use of ergogenic supplements known to influence protein metabolism.</p> <h3>Training Protocol</h3> <p>Both groups trained three sessions per week on non-consecutive days for 10 weeks under the supervision of qualified strength coaches. The multi-joint (MJ) group performed only compound exercises targeting the upper body: lat pulldown and bench press, chosen to tax the elbow flexors and extensors as synergists. The combined group (MJ+SJ) performed the same compound movements with the addition of barbell curl and triceps pulley extension as dedicated isolation exercises.</p> <p>All sessions were equalized for effort using sets of 8-12 repetitions to volitional failure, and loads were progressively adjusted to maintain the prescribed repetition range. Rest intervals between sets were standardized at 90 seconds. Total <a href="/terms/training-volume/" class="term-link" data-slug="training-volume" title="training volume">training volume</a> (sets x repetitions x load) was recorded to confirm protocol adherence [1].</p> <h3>Outcome Measures</h3> <p>Muscle <a href="/terms/cross-sectional-area/" class="term-link" data-slug="cross-sectional-area" title="cross-sectional area">cross-sectional area</a> (CSA) of the elbow flexors (biceps brachii) and extensors (triceps brachii) was quantified using B-mode ultrasound imaging at the mid-belly of each muscle. Images were captured at pre- and post-intervention time points. Maximal dynamic strength was assessed using the <a href="/terms/one-repetition-maximum/" class="term-link" data-slug="one-repetition-maximum" title="one-<a href="/terms/repetition-maximum/" class="term-link" data-slug="repetition-maximum" title="repetition maximum">repetition maximum</a>">one-repetition maximum</a> (1RM) protocol in the lat pulldown and triceps pushdown under standardized conditions. All assessors were blinded to group allocation.</p> <h3>Statistical Analysis</h3> <p>Between- and within-group differences were evaluated using a two-way repeated-measures analysis of variance (ANOVA). Effect sizes (<a href="/terms/effect-size/" class="term-link" data-slug="effect-size" title="Cohen&#x27;s d">Cohen&#x27;s d</a>) were calculated to provide a measure of practical significance. Statistical significance was set at p 0.05.</p>

Results

<h2>Results</h2> <p>Both training groups demonstrated statistically significant improvements in muscle <a href="/terms/cross-sectional-area/" class="term-link" data-slug="cross-sectional-area" title="cross-sectional area">cross-sectional area</a> and maximal strength relative to baseline. However, no significant between-group differences were detected for any primary outcome variable.</p> <h3>Muscle Cross-Sectional Area</h3> <p>Elbow flexor CSA increased by approximately 6.0% in the MJ group and 5.5% in the MJ+SJ group, a difference that did not reach statistical significance (p 0.05). Similarly, elbow extensor CSA increased by approximately 5.8% in MJ and 6.2% in MJ+SJ, again with no significant between-group difference. Effect sizes for between-group comparisons were small (<a href="/terms/effect-size/" class="term-link" data-slug="effect-size" title="Cohen&#x27;s d">Cohen&#x27;s d</a> 0.3), indicating negligible practical differences in hypertrophic outcomes [1].</p> <h3>Muscular Strength</h3> <p>Lat pulldown <a href="/terms/one-repetition-maximum/" class="term-link" data-slug="one-repetition-maximum" title="1RM">1RM</a> improved significantly in both groups, with the MJ group gaining approximately 16.4 kg and the MJ+SJ group gaining 17.1 kg over 10 weeks. Triceps pushdown 1RM likewise improved in both conditions. No statistically significant interaction effects were detected, confirming that the addition of isolation exercises provided no measurable strength advantage above and beyond the multi-joint protocol alone [1].</p> <h3>Adherence and Volume</h3> <p>Training adherence exceeded 95% in both groups. When total volume was analyzed, the MJ+SJ group naturally accumulated a greater overall <a href="/terms/training-volume/" class="term-link" data-slug="training-volume" title="training volume">training volume</a> per session due to the additional exercises. Despite this volumetric difference, the outcomes remained comparable, suggesting that the additional volume from isolation exercises contributed no incremental adaptive benefit in this population.</p> <p>These results indicate that the muscular demands placed on the elbow flexors and extensors during compound pulling and pressing movements are sufficient to drive meaningful <a href="/terms/muscle-hypertrophy/" class="term-link" data-slug="muscle-hypertrophy" title="hypertrophy">hypertrophy</a> and strength development in previously untrained individuals, at least over a 10-week training period.</p>

Discussion

<h2>Discussion</h2> <p>The primary finding of this investigation — that the addition of single-joint isolation exercises to a multi-joint resistance training program does not confer statistically or practically meaningful additional benefits in <a href="/terms/muscle-hypertrophy/" class="term-link" data-slug="muscle-hypertrophy" title="hypertrophy">hypertrophy</a> or strength for untrained individuals — has important implications for evidence-based program design.</p> <h3>Mechanistic Considerations</h3> <p>The results suggest that compound exercises such as the lat pulldown and bench press generate sufficient <a href="/terms/mechanical-tension/" class="term-link" data-slug="mechanical-tension" title="mechanical tension">mechanical tension</a> and <a href="/terms/metabolic-stress/" class="term-link" data-slug="metabolic-stress" title="metabolic stress">metabolic stress</a> in synergist muscles to produce adaptations comparable to those achieved with dedicated isolation work. The elbow flexors, for instance, are heavily recruited during lat pulldown performance, as evidenced by <a href="/terms/electromyography/" class="term-link" data-slug="electromyography" title="EMG">EMG</a> studies demonstrating high biceps brachii activation during pulling movements [2]. The high sensitivity of untrained muscle to any consistent mechanical stimulus likely explains why even indirect loading through compound movements is adequate to drive near-maximal adaptive responses in this population.</p> <h3>Population Specificity</h3> <p>It is essential to interpret these findings within the appropriate population context. The participants were untrained, a group known to respond robustly to virtually any structured resistance training stimulus — a phenomenon referred to as the "beginner effect." In trained individuals with higher baseline muscular development, the adaptive stimulus provided by compound movements may be insufficient to continue driving growth in specific muscle groups, potentially necessitating the targeted isolation work that more experienced lifters commonly employ [3].</p> <h3>Practical Implications and Limitations</h3> <p>From a practical standpoint, these findings validate MJ-only training as an efficient and effective approach for beginner populations. Coaches and clinicians working with time-constrained or novice clients can confidently prioritize compound movements without sacrificing meaningful adaptive outcomes. The 10-week study duration represents a limitation, as longer-term investigations may detect divergent responses as participants accumulate training experience and approach more advanced stages of development.</p> <p>Future research should examine these relationships in intermediate and advanced trainees, as well as explore whether specific anatomical regions (e.g., the long head of the biceps) respond differentially to isolation versus compound loading over extended training periods [1].</p>